Vivo ouano biography samples
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Biogenic nanoparticles for managing salinity stress-related crop and environmental risks: realistic applications and challenges
1 Introduction
Soil salting is a global issue that affects approximately 1100 Mha of land, or approximately 7% of the Earth’s surface area [1, 2]. Soil salinization is caused by natural geochemical processes and human activities [3]. Primary salinization events have negatively impacted a large portion of cultivated lands due to atmospheric deposition, increasing temperatures, elevating sea levels, and saltwater seepage into clean water reservoirs. Moreover, supplementary salinization is thought to aggravate 30% of irrigated areas because of inadequate fertilizer use, improper management techniques, and intensive agriculture [4,5,6,7].
Significant losses in agricultural output, especially in arid and semiarid areas, are caused by a shortage of fresh water for irrigation, and the continuous deterioration of agricultural fields is correlated with salt str
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Published in sista edited form as: Cell Rep. 2019 Apr 30;27(5):1334–1344.e6. doi: 10.1016/j.celrep.2019.04.017
SUMMARY
Lafora disease (LD) and adult polyglucosan body disease (APBD) are glycogen storage diseases characterized by a pathogenic buildup of insoluble glycogen. Mechanisms causing glycogen insolubility are poorly understood. Here, in two mouse models of LD (Epm2a−/− and Epm2b−/−) and one of APBD (Gbe1ys/ys), the separation of soluble and insoluble muscle glycogen is described, enabling separate analysis of each fraction. Total glycogen is increased in LD and APBD mice, which, together with abnormal chain length and molekyl size distributions, is largely if not fully attributed to insoluble glycogen. Soluble glycogen consists of molecules with distinct chain length distributions and differential corresponding solubility, providing a mechanistic link between soluble and insoluble glycogen in vivo. Phos
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Published in sista edited form as: Biomaterials. 2020 Apr 1;249:120011. doi: 10.1016/j.biomaterials.2020.120011
Abstract
The performance of clinical synthetic small diameter vascular grafts remains disappointing due to the fast occlusion caused by thrombosis and intimal hyperplasia formation. Poly(vinyl alcohol) (PVA) hydrogels have tunable mechanical properties and a low thrombogenic surface, which suggests its potential value as a small diameter vascular graft material. However, PVA does not support cell adhesion and thus requires surface modification to encourage endothelialization. This study presents a modification of PVA with fucoidan. Fucoidan is a sulfated polysaccharide with anticoagulant and antithrombotic properties, which was shown to potentially increase endothelial cell adhesion and proliferation. By mixing fucoidan with PVA and co-crosslinked by sodium trimetaphosphate (STMP), the modification was achieved withou